PMID-11923450[0] Synchronized neuronal discharge in the basal ganglia of parkinsonian patients is limited to oscillatory activity.
- simultaneous recording for pallidotomy or STN DBS.
- In the five pallidotomy patients without limb tremor during the procedure, none of the 73 GPi pairs and 15 GPe pairs displayed synchronous activity. we got the same result
- In the three pallidotomy patients with limb tremor, 6 of 21 GPi pairs and 5 of 29 GPe pairs displayed oscillatory synchronization in the frequency range of the ongoing limb tremor (3-6 Hz) or at higher frequencies (15-30 Hz).
- Synchronized activity was not observed in the SNr (10 pairs).
____References____
[0] Levy R, Hutchison WD, Lozano AM, Dostrovsky JO, Synchronized neuronal discharge in the basal ganglia of parkinsonian patients is limited to oscillatory activity.J Neurosci 22:7, 2855-61 (2002 Apr 1) |
|