PMID-2402638[] Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
- MPTP monkeys.
- Guided by the rate hypothesis (which is probably false, but no matter!)
- The lesions reduced all of the major motor disturbances in the contralateral limbs, including akinesia, rigidity, and tremor.
- the study that opened up a treatment - and helped many people!!
- wasn't the first DBS surgery done in 1983 by Benabid? No, it was 1993!
____References____
|