Super-Photostable Phosphole-Based Dye for Multiple-Acquisition Stimulated Emission Depletion Imaging
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- Use the electron withdrawing ability of a phosphole group (P = O) to reduce photobleaching
- Derived from another photostable dye, C-Naphox, only with a different mechanism of fluorescence -- pi-pi* transfer rather than intramolecular charge transfer (ICT).
- Much more stable than Alexa 488 (aka sulfonated fluorescein, which is not the most stable dye..)
- Suitable for multiple STED images, unlike the other dyes. (Note!)
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