{1515} revision 1 modified: 07-16-2020 14:06 gmt

Super-Photostable Phosphole-Based Dye for Multiple-Acquisition Stimulated Emission Depletion Imaging

  • Use the electron withdrawing ability of a phosphole group (P = O) to reduce photobleaching
  • Derived from another photostable dye, C-Naphox, only with a different mechanism of fluorescence -- pi-pi* transfer rather than intramolecular charge transfer (ICT).
  • Much more stable than Alexa 488 (aka sulfonated fluorescein, which is not the most stable dye..)
  • Suitable for multiple STED images, unlike the other dyes. (Note!)