PMID-19233172[0] Synchronisation in the beta frequency-band - The bad boy of parkinsonism or an innocent bystander?
- Excessive synchronisation of basal ganglia neuronal activity in the beta frequency band has been implicated in Parkinson's disease
- However, the extent to which beta synchrony has a mechanistic (rather than epiphenomenal) role in parkinsonism remains unclear, and the suppression of this activity by deep brain stimulation is contentious.
PMID-16289053[1] Intra-operative STN DBS attenuates the prominent beta rhythm in the STN in Parkinson's disease.
- Beta rhythm for them = 11-30Hz. Observed in the LFP recorded from the DBS electrode itself.
- This study shows for the first time that STN DBS attenuates the power in the prominent beta band recorded in the STN of patients with PD.
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[0] Eusebio A, Brown P, Synchronisation in the beta frequency-band - The bad boy of parkinsonism or an innocent bystander?Exp Neurol no Volume
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(2009 Feb 20) |
[1] Wingeier B, Tcheng T, Koop MM, Hill BC, Heit G, Bronte-Stewart HM, Intra-operative STN DBS attenuates the prominent beta rhythm in the STN in Parkinson's disease.Exp Neurol 197:1, 244-51 (2006 Jan) |
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