PMID-15576886[0] Reverberation, storage, and postsynaptic propagation of memories during sleep
- Many references in the first paragraph! They should switch to the [n] notation; the names are disruptive.
- Show reverberation (is this measured in a scale-invariant way?) increases after novel object is placed in cage. Recorded from a single rat for up to 96 hours.
- also looked at Zif-268 activation in the cortex (autoradiogram);
- Previous results showed that Zif-268 levels are up-regulated in REM but not SWS in the hippocampus and cerebral cortex of exposed animals. (Ribeiro 1999)
- hippocampal inactivation during REM sleep blocked zif-268 upregulation.
- quote: "Increased activity is necessary but not sufficient to induce zif-268 expression, which also requires calcium inflow via NMDA channels and phosphorilation of the cAMP response element-binding protein (CREB)"
- Sleep deprivation is much more detrimental to implicit than to explicit memory consolidation (Fowler et al. 1973; Karni et al. 1994; Smith 1995, 2001; Stickgold et al. 2000a; Laureys et al. 2002; Walker et al. 2002; Maquet et al. 2003; Mednick et al. 2003)
____References____
[0] Ribeiro S, Nicolelis MA, Reverberation, storage, and postsynaptic propagation of memories during sleep.Learn Mem 11:6, 686-96 (2004 Nov-Dec) |
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