PMID-17409479[0] Thin microelectrodes reduce GFAP expression in the implant site in rodent somatosensory cortex.
- Implanted 12 um and 25 um polymide coated stainless steel
- Wires coated with poly-glycolic acid (PGA) to facilitate implantation.
- Only looked to 4 weeks.
- 12 um implants significantly less GFAP (astrocyte) reactivity at 4 weeks, no difference at 2 weeks (figure 9 & 10).
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- B = bare, P = PGA coated.
- Can use to bolster the idea that smaller implants are less irritating.
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[0] Stice P, Gilletti A, Panitch A, Muthuswamy J, Thin microelectrodes reduce GFAP expression in the implant site in rodent somatosensory cortex.J Neural Eng 4:2, 42-53 (2007 Jun) |
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