PMID-17189946[0] Cortico-hippocampal interaction during up-down states and memory consolidation.
- (from the associated review) Good pictorial description of how the hippocampus may impinge order upon the cortex:
- During sleep the cortex is spontaneously and randomly active. Hippocampal activity is similarly disorganized.
- During waking, the mouse/rat moves about in the environment, activating a sequence of place cells. The weights of the associated place cells are modified to reflect this sequence.
- When the rat falls back to sleep, the hippocampus is still not random, and replays a compressed copy of the day's events to the cortex, which can then (and with other help, eg. ACh), learn/consolidate it.
- see [1].
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